| Fri, 11 Sep 2026 | Angermayer Christian | director, 10 percent owner | D-Return | 1,799,302 | — |
| Fri, 11 Sep 2026 | Angermayer Christian | director, 10 percent owner | D-Return | 53,398,214 | — |
| Fri, 11 Sep 2026 | Angermayer Christian | director, 10 percent owner | D-Return | 559,232 | — |
| Fri, 11 Sep 2026 | Smiley Andrea Heslin | director | D-Return | 4,666 | — |
| Fri, 11 Sep 2026 | Kalali Amir H | director | D-Return | 4,666 | — |
| Fri, 11 Sep 2026 | Short Glenn Frank | officer: Chief Scientific Officer | D-Return | 42,333 | — |
| Fri, 11 Sep 2026 | Barrett Christopher Ryan Cave | officer: See remarks | D-Return | 155,066 | — |
| Fri, 11 Sep 2026 | Johnson Anne Nagengast | officer: Chief Accounting Officer | D-Return | 140,045 | — |
| Fri, 11 Sep 2026 | Rao Srinivas | director, officer: See remarks | D-Return | 3,500 | — |
| Fri, 11 Sep 2026 | Rao Srinivas | director, officer: See remarks | D-Return | 212,942 | — |
| Fri, 11 Sep 2026 | Craig Kevin James | officer: Chief Medical Officer | D-Return | 8,437 | — |
| Tue, 7 Jul 2026 | HERSHBERG ROBERT | director | S-Sale | 100,000 | $496K |
| Tue, 7 Jul 2026 | HERSHBERG ROBERT | director | M-Exempt | 51,142 | $69.04K |
| Tue, 7 Jul 2026 | HERSHBERG ROBERT | director | M-Exempt | 48,858 | $65.96K |
| Fri, 26 Jun 2026 | Kochendoerfer Gerd | officer: Chief Operating Officer | S-Sale | 50,000 | $250K |
| Fri, 26 Jun 2026 | Kochendoerfer Gerd | officer: Chief Operating Officer | M-Exempt | 50,000 | $80K |
| Thu, 25 Jun 2026 | Craig Kevin James | officer: Chief Medical Officer | S-Sale | 42,579 | $192.03K |
| Thu, 25 Jun 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 33,051 | $49.58K |
| Thu, 25 Jun 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 9,528 | $11.24K |
| Mon, 20 Apr 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 15,299 | $28.15K |
| Mon, 20 Apr 2026 | Craig Kevin James | officer: Chief Medical Officer | S-Sale | 42,579 | $212.9K |
| Mon, 20 Apr 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 27,280 | $40.92K |
| Wed, 8 Apr 2026 | Apeiron Investment Group Ltd. | 10 percent owner | M-Exempt | 410,162 | $672.67K |
| Wed, 8 Apr 2026 | Apeiron Investment Group Ltd. | 10 percent owner | M-Exempt | 103,000 | $138.02K |
| Wed, 8 Apr 2026 | Apeiron Investment Group Ltd. | 10 percent owner | M-Exempt | 46,070 | $86.61K |
| Fri, 20 Mar 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 23,776 | $35.66K |
| Fri, 20 Mar 2026 | Craig Kevin James | officer: Chief Medical Officer | M-Exempt | 76,224 | $89.94K |
| Fri, 20 Mar 2026 | Craig Kevin James | officer: Chief Medical Officer | S-Sale | 100,000 | $355K |
| Fri, 2 Jan 2026 | Feilding-Mellen Cosmo | director | S-Sale | 39,594 | $154.42K |
| Wed, 5 Nov 2025 | Feilding-Mellen Cosmo | director | A-Award | 7,702,990 | — |
