| Thu, 1 Oct 2026 | Garland J. Scott | director | M-Exempt | 13,000 | $201.11K |
| Thu, 1 Oct 2026 | Garland J. Scott | director | S-Sale | 13,000 | $606.72K |
| Thu, 17 Sep 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 2,916 | $145.89K |
| Thu, 17 Sep 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 240 | $12.36K |
| Thu, 17 Sep 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 3,982 | $59.13K |
| Thu, 17 Sep 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 289 | $14.88K |
| Thu, 17 Sep 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 1,844 | $93.51K |
| Thu, 17 Sep 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 3,535 | $176.85K |
| Thu, 17 Sep 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | M-Exempt | 5,000 | $12.4K |
| Thu, 17 Sep 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 2,194 | $111.27K |
| Mon, 17 Aug 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 1,388 | $82.38K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | M-Exempt | 5,000 | $12.4K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 1,100 | $65.28K |
| Mon, 17 Aug 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 4,630 | $270.17K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 1,100 | $65.28K |
| Mon, 17 Aug 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 1,388 | $82.38K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | M-Exempt | 5,000 | $12.4K |
| Mon, 17 Aug 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 4,630 | $270.17K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 3,900 | $227.65K |
| Mon, 17 Aug 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 3,900 | $227.65K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 23,364 | $346.96K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 27,567 | $696.89K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 20,491 | $460.43K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 20,491 | $460.43K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | S-Sale | 158,795 | $9.56M |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 87,373 | $216.69K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | S-Sale | 158,795 | $9.56M |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 23,364 | $346.96K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 27,567 | $696.89K |
| Tue, 4 Aug 2026 | Derynck Mika K | director | M-Exempt | 87,373 | $216.69K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 63 | $3.4K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 2,184 | $116.67K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | M-Exempt | 1,072 | $2.66K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 324 | $16.19K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 369 | $19K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 2,564 | $134.14K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 2,638 | $140.82K |
| Fri, 17 Jul 2026 | Hohl Benjamin | officer: CHIEF FINANCIAL OFFICER | S-Sale | 123 | $6.63K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | M-Exempt | 5,000 | $12.4K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 231 | $11.56K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 459 | $23.66K |
| Fri, 17 Jul 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 2,063 | $108.08K |
| Mon, 6 Jul 2026 | Kunkel Lori Anne | director | S-Sale | 4,111 | $205.48K |
| Mon, 6 Jul 2026 | Kunkel Lori Anne | director | S-Sale | 5,889 | $299.42K |
| Mon, 22 Jun 2026 | ORBIMED ADVISORS LLC | 10 percent owner | S-Sale | 1,477 | $66.47K |
| Mon, 22 Jun 2026 | ORBIMED ADVISORS LLC | 10 percent owner | S-Sale | 787,024 | $35.72M |
| Mon, 22 Jun 2026 | ORBIMED ADVISORS LLC | 10 percent owner | S-Sale | 46,776 | $2.1M |
| Mon, 22 Jun 2026 | ORBIMED ADVISORS LLC | 10 percent owner | S-Sale | 24,846 | $1.13M |
| Wed, 17 Jun 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | S-Sale | 1,133 | $50.69K |
| Wed, 17 Jun 2026 | Collins Helen Louise | officer: CHIEF MEDICAL OFFICER | M-Exempt | 5,000 | $12.4K |
