| Date | Name | Role | Type | Shares | Value |
|---|---|---|---|---|---|
| Mon, 17 Aug 2026 | Smith Margaret Ekins | — | — | 0 | $0 |
| Fri, 12 Jun 2026 | Fitzpatrick Alexander A | officer: Chief Legal Officer | S-Sale | 3,355 | $33.55K |
| Fri, 12 Jun 2026 | Karas Eric | officer: Chief Commercial Officer | M-Exempt | 25,000 | $37.5K |
| Fri, 12 Jun 2026 | Karas Eric | officer: Chief Commercial Officer | S-Sale | 25,000 | $250K |
| Thu, 13 Nov 2025 | Dorsey Brian | officer: Chief Operating Officer | S-Sale | 21,828 | $190.12K |
| Thu, 13 Nov 2025 | Dorsey Brian | officer: Chief Operating Officer | M-Exempt | 21,828 | $13.97K |
| Wed, 12 Nov 2025 | Shah Pratik | director |
| G-Gift |
| 250,000 |
| $0 |
| Wed, 12 Nov 2025 | Shah Pratik | director | G-Gift | 100,000 | $0 |
| Wed, 12 Nov 2025 | Chakma Justin | officer: Chief Business Officer | M-Exempt | 30,000 | $25.2K |
| Wed, 12 Nov 2025 | Chakma Justin | officer: Chief Business Officer | S-Sale | 30,000 | $267.3K |
| Wed, 12 Nov 2025 | Chakma Justin | officer: Chief Business Officer | S-Sale | 136,380 | $1.21M |
| Holder | Shares | % out | Change |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | 10,860,977 | 10.9% | +0 |
| Rubric Capital Management LP | 8,540,861 | 8.6% | +540,861 |
| ORBIMED ADVISORS LLC | 8,288,510 | 8.3% | +0 |
| DEERFIELD MANAGEMENT COMPANY, L.P. | 7,503,812 | 7.5% | +0 |
| BlackRock, Inc. | 5,311,319 | 5.3% | +299,065 |
| Tyro Capital Management LLC | 4,459,337 | 4.5% | +1,490,738 |
| Aberdeen Group plc | 4,170,629 | 4.2% | +57,012 |
| SR One Capital Management, LP | 4,012,903 | 4.0% | +0 |
| STATE STREET CORP | 3,730,623 | 3.8% | +85,657 |
| Capital World Investors | 2,754,931 | 2.8% | — |
| VANGUARD CAPITAL MANAGEMENT LLC | 2,553,528 | 2.6% | +11,024 |
| MILLENNIUM MANAGEMENT LLC | 2,400,937 | 2.4% | −3,581,982 |
| UBS Group AG | 1,939,654 | 2.0% | −320,671 |
| GEODE CAPITAL MANAGEMENT, LLC |
| 1,699,017 |
| 1.7% |
| +172,193 |
| BOOTHBAY FUND MANAGEMENT, LLC | 1,601,504 | 1.6% | +1,350,907 |
